Chungnam National University.

Graduate School of New Drug Discovery and Development.

충남대학교 신약전문대학원

학연교원

김기영 프로필 사진
이름
김기영
담당업무
신약개발/약리학/세포생물학
직장 전화
사무실
한국화학연구원, 의약바이오연구본부 희귀질환치료기술연구센터, E3동 111-3호

실험실

약리학 교실 (042-860-7471)
메일주소:kykim@krict.re.kr

학력

석사 : 1996~1998 부산대학교 생물학 (동물생리학)

박사 : 1998~2002 부산대학교 생물학 동물학전공 (내분비학)

경력

2002 ~ 2003  부산대학교 의과대학 약리학교실 Post-Doc
2003 ~ 2013  한국화학연구원 선임연구원
2011 ~ 2016   과학기술연합대학원대학교(의약화학 및 약품화학) 겸임교원
2013 ~ 현재   한국화학연구원 책임연구원

논문

1. Optimization of cyclic sulfamide derivatives as 11β-hydroxysteroid dehydrogenase 1 inhibitors for the potential treatment of ischemic brain injury	BIOORGANIC & MEDICINAL CHEMISTRY LETTERS	Vol.30,126787p~126792p	2020.01.15

2. Development of a Three-Dimensional in Vitro Co-Culture Model to Increase Drug Selectivity for Humans	Diabetes Obesity and Metabolism	Vol.22,1302p~1315p	2020.04.16

3. A Novel Selective 11b-HSD1 Inhibitor, (E)-4-(2-(6-(2,6-Dichloro-4-(Trifluoromethyl)Phenyl)-4-Methyl-1,1-Dioxido-1,2,6-Thiadiazinan-2-yl)Acetamido)Adamantan-1-Carboxamide (KR-67607), Prevents BAC-Induc	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	Vol.21,3929p~0p	2020.05.25

4. Magnolol induces adipogenic differentiation in human skin	The British journal of dermatology	Vol.183,584p~586p	2020.09.01

5. Toxicity Assessment of SiO2 and TiO2 in Normal Colon Cells, In Vivo and in Human Colon Organoids	Molecules	Vol.25,3594p~0p	2020.08.11

6. iTRAQ-Based Quantitative Proteomic Comparison of 2D and 3D Adipocyte Cell Models Co-cultured with Macrophages Using Online 2D-nanoLC-ESI-MS/MS	Scientific Reports	Vol.9,16746p~0p	2019.11.14

7. Protective effect of a novel selective 11β-HSD1 inhibitor on eye ischemia-reperfusion induced glaucoma	BIOCHEMICAL PHARMACOLOGY	Vol.169,113632p~113642p	2019.09.05

8. Anticancer effect of XAV939 is observed by inhibiting lactose dehydrogenase A in a 3-dimensional culture of colorectal cancer cells.	Oncology Letters	Vol.2019,4858p~4864p	2019.09.02

9. 요엽후박나무 추출물의 입술 주름 개선에 대한 연구	대한화장품학회지	Vol.45,95p~103p	2019.03.19

10. Development of in vitro three-dimensional co-culture system for metabolic syndrome therapeutic agents	Diabetes Obesity and Metabolism	Vol.21,1146p~1157p	2019.01.04

11. Quantitative proteomic analysis of 2D and 3D cultured colorectal cancer cells: Profiling of tankyrase inhibitor XAV939-induced proteome	Scientific Reports	Vol.8,13255p~0p	2018.11.22

12. Development of a parallel microbore hollow fiber enzyme reactor platform for online 18O-labeling: Application to lectin-specific lung cancer N-glycoproteome	Journal of Chromatography B	Vol.1100,58p~64p	2018.10.02

13. Cyp7a1 is continuously increased with disrupted Fxr-mediated feedback inhibition in hypercholesterolemic TALLYHO/Jng mice	Biochimica et Biophysica Acta-Momelular and cell Biology of Lipids	Vol.1863,20p~25p	2018.01.15

특허

1. 인간 유래 세포를 포함하는 3 차원 세포배양 구조체, 이를 이용한 3 차원 세포배양 방법, 및 이를 이용한 약물 스크리닝 방법	20200914	2157905	대한민국	

2. 설치류 유래의 지방 전구세포를 포함하는 3 차원 세포배양 구조체, 이를 이용한 3 차원 세포배양 방법, 및 이를 이용한 약물 스크리닝 방법	20200525	2116741	대한민국