학사: 1986~1990, 고려대학교 화학과
석사: 1990~1992, 고려대학교 화학과 유기화학전공
박사: 1997~2001, Case Western Reserve University, Department of Chemistry 이학박사
경력
1992~1997: 한화그룹종합연구소 주임연구원
2001~2003: University of Michigan, Department of Chemistry, Post Doc.
2003~현재: 한국화학연구원 의약화학연구센터 책임연구원
주요 연구 활동
Medicinal chemistry for development of drug candidates
Discovery of anticancer and osteoporosis agents
Total synthesis of natural products
Development of new methodology for the carbon-carbon formation by using metal-catalyzed reaction
실험실 및 메일 주소
의약화학연구실 (042-860-7025)
메일주소:heojn@krict.re.kr
논문
1. Efficient synthesis of dibenzazepine lactams via a sequential Pd-catalyzed amination and aldol condensation reaction TETRAHEDRON LETTERS Vol.61,151536p~0p 2020.02.27
2. A Two-Photon Probe for TNF-α. Assessment of the Transmembrane TNF-α Level in Human Colon Tissue by Two-Photon Microscopy ANALYTICAL CHEMISTRY Vol.2019,15769p~15776p 2019.10.31
3. αVβ3-Targeted Delivery of Camptothecin-Encapsulated Carbon Nanotube-Cyclic RGD in 2D and 3D Cancer Cell Culture JOURNAL OF PHARMACEUTICAL SCIENCES Vol.108,3704p~3712p 2019.09.02
4. Identification of Natural Products as Novel PI3Kb Inhibitors through Pharmacophore-based Virtual Screening 대한화학회지 Vol.39,294p~299p 2018.11.26
5. A Natural Compound, Aristoyagonine, Is Identified as a Potent Bromodomain Inhibitor by Mid-Throughput Screening. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Vol.503,882p~887p 2018.07.01
