Chungnam National University.

Graduate School of New Drug Discovery and Development.

충남대학교 신약전문대학원

학연교원

이정현  프로필 사진
이름
이정현
직위(직급)
책임연구원
직장 전화
사무실
한국화학연구원 신약정보기술연구센터 E4연구동 102호

학력

학사: 부산대학교 분자생물학 
석사: 부산대학교 약리학
박사: 부산대학교 약리학

경력

2008 ~ 2011 : 미국 Harvard 의대 Post-Doc 
2011 ~ 2019 : 한국화학연구원 선임연구원 
2017 ~ 2020 : 과학기술연합대학원대학교 겸임교원 
2019 ~  현 재 : 한국화학연구원 책임연구원
2022. 3. ~      : 충남대학교 신약전문대학원 학연교원

실험실

042-860-7448

논문

KR-31831 improves survival and protects hematopoietic cells and radiosensitive tissues against radiation-induced injuries in mice. Biomedicine & Pharmacotherapy. Vol.146, 112350. (2022.02.01)

PredMS: a random Forest model for predicting metabolic stability of drug candidates in human liver microsomes. Bioinformatics. Vol. 38, 364-368. (2022.01.15.)

Identification of new target proteins of a Urotensin-II receptor antagonist using transcriptome-based drug repositioning approach. Scientific Reports. Vol.11, 17138. (2021.08.24.)

KR-39038, a novel GRK5 inhibitor, attenuates cardiac hypertrophy and improves cardiac function in heart failure. Biomolecules & Therapeutics. Vol. 28, 482-489 (2020.08.29.)

DeepHIT: a deep learning framework for prediction of hERG-induced cardiotoxicity. Bioinformatics. Vol. 36, 3049-3055. (2020.05.15.)

Optimization of cyclic sulfamide derivatives as 11beta-hydroxysteroid dehydrogenase 1 inhibitors for the potential treatment of ischemic brain injury. Bioorganic & Medicinal Chemistry Letters. Vol. 30, 126787. (2020.01.15.)

Icariin protects against radiation-induced mortality and damage in vitro and in vivo.
International Journal of Radiation Biology. Vol. 95, 1094-1102. (2019.04.19)

DITMD-induced mitotic defects and apoptosis in tumor cells by blocking the polo-box domain-dependent functions of polo-like kinase 1. European Journal of Pharmacology. Vol. 847. 113-122. (2019.03.15)